Onderzoek VS gezondheid rashond versus mixed breeds
Geplaatst: 04 dec 2013 19:57
Kijk Dier en Recht is zo dol op literatuuronderzoek (daar is de Rashondenwijzerwijzer op gebaseerd), hebben ze toch iets gemist: ze hadden de Wetenschapswinkel van de Wur niet hoeven inschakelen:
Purebred dogs no more at risk of inherited diseases than crossbreeds, new study says
Created: 04/07/2013
AN AMERICAN study has cast aside the common assumption that a mixed breed is always healthier than a pedigree dog.
The study, researched and collated by Bellumori et al. (2013), indicates that a dog’s risk of a specific inherited disease is more likely to be influenced by the disease itself, rather than by the risk of being a specific breed or crossbreed.
Medical records from 27,000 dogs over the course of 15 years at the University of California Veterinary Medical Teaching Hospital, in Davis, California, were collected and evaluated for 24 known genetic disorders such as cancer, dysplasia, cardiac problems, patellar luxation and epilepsy.
The study describes that the results indicated that ‘genetic disorders were individual in their expression throughout the dog population’ and that ‘some genetic disorders were present with equal prevalence among all dogs in the study, regardless of purebred or mixed breed status’.
Of the 24 different disorders assessed, 13 had no significant difference in the mean proportion of purebred and mixed breed dogs, when matched by age, sex, and body weight. This includes some diseases that had previously been associated predominantly with purebred dogs, such as osteosarcoma, mitral valve disease, hip dysplasia, and patellar luxation.
However, ten of the disorders were found to be more prominent in purebred dogs. These were aortic stenosis, dilated cardiomyopathy, hypothyroidism, elbow dysplasia, intervertebral disk disease, atopy, dermatitis, bloat, cataracts, epilepsy and shunt.
Within the study, specific breeds were also listed with their probability of contracting one of the ten disorders. This was calculated by the percentage of dogs of the relative breeds that were affected.
Intervertebral disk disease showed the highest percentages. At the top was the Dachshund group with 34.92 per cent, followed by the French Bulldog with 27.06 per cent; Pekingese, 20.59 per cent; Pembroke Welsh Corgi, 15.11 per cent; Dobermann, 12.70 per cent and the mixed breed, 4.43 per cent.
In the elbow dysplasia category the Bernese Mountain Dog had a 13.91 per cent probability; Newfoundland, 10.28 per cent; Mastiff 6.5 per cent; Rottweiler, 6.31 per cent; Anatolian Shepherd, 5.41 per cent and the mixed breed showed a 0.90 per cent probability.
The Dobermann appeared three times and came out in the top five probabilities for hypothyroidism, dilated cardiomyopathy and intervertebral disk disease.
For such disorders that affected purebred dogs in a higher percentage, researchers describe that this will have occurred more recently, such as when specific gene pools were developed or showed characteristics of particular lineages.
The study continues by explaining that ‘every disorder was seen in the mixed breed population’ and concluded that on the ‘basis of the data and analysis, the proportion of mixed-breed and purebred dogs affected by genetic disorders may be equal or differ, depending on the specific disorder’.
In particular, mixed breeds showed high percentages of being affected by cruciate ligament ruptures and researchers believe the reason for this is the crossing of certain breeds with varying skeletal structures.
The Kennel Club, who were pleased to read the study, believe that although the study was conducted overseas that it can ultimately affect all dogs.
Caroline Kisko, Kennel Club secretary explained: "This will ultimately impact all dogs, as there were no conditions found solely in purebred dogs. In addition, there was no single breed that was over-represented as a higher risk in the ten disorders assessed.
"Of the cancers assessed, specifically, there was no significant difference in risk between purebred and mixed breed dogs. Overall, the results indicated that genetic disorders were individual in their expression throughout the whole dog population, and that for some specific conditions there was a distinction between purebred and mixed breed dogs, and for other conditions, there was no difference to risk at all.
"We hope that the study will help people to make the right choices when buying a puppy and ask for relevant health checks no matter if they are purebred dogs or crossbreed dogs.”
The purebred dogs in the tests complied with the breed definition set out by the American Kennel Club.
- See more at: http://www.dogworl ... 4so8m.dpuf
http://www.dogworld.co.uk/product.php/95854
Purebred dogs no more at risk of inherited diseases than crossbreeds, new study says
Created: 04/07/2013
AN AMERICAN study has cast aside the common assumption that a mixed breed is always healthier than a pedigree dog.
The study, researched and collated by Bellumori et al. (2013), indicates that a dog’s risk of a specific inherited disease is more likely to be influenced by the disease itself, rather than by the risk of being a specific breed or crossbreed.
Medical records from 27,000 dogs over the course of 15 years at the University of California Veterinary Medical Teaching Hospital, in Davis, California, were collected and evaluated for 24 known genetic disorders such as cancer, dysplasia, cardiac problems, patellar luxation and epilepsy.
The study describes that the results indicated that ‘genetic disorders were individual in their expression throughout the dog population’ and that ‘some genetic disorders were present with equal prevalence among all dogs in the study, regardless of purebred or mixed breed status’.
Of the 24 different disorders assessed, 13 had no significant difference in the mean proportion of purebred and mixed breed dogs, when matched by age, sex, and body weight. This includes some diseases that had previously been associated predominantly with purebred dogs, such as osteosarcoma, mitral valve disease, hip dysplasia, and patellar luxation.
However, ten of the disorders were found to be more prominent in purebred dogs. These were aortic stenosis, dilated cardiomyopathy, hypothyroidism, elbow dysplasia, intervertebral disk disease, atopy, dermatitis, bloat, cataracts, epilepsy and shunt.
Within the study, specific breeds were also listed with their probability of contracting one of the ten disorders. This was calculated by the percentage of dogs of the relative breeds that were affected.
Intervertebral disk disease showed the highest percentages. At the top was the Dachshund group with 34.92 per cent, followed by the French Bulldog with 27.06 per cent; Pekingese, 20.59 per cent; Pembroke Welsh Corgi, 15.11 per cent; Dobermann, 12.70 per cent and the mixed breed, 4.43 per cent.
In the elbow dysplasia category the Bernese Mountain Dog had a 13.91 per cent probability; Newfoundland, 10.28 per cent; Mastiff 6.5 per cent; Rottweiler, 6.31 per cent; Anatolian Shepherd, 5.41 per cent and the mixed breed showed a 0.90 per cent probability.
The Dobermann appeared three times and came out in the top five probabilities for hypothyroidism, dilated cardiomyopathy and intervertebral disk disease.
For such disorders that affected purebred dogs in a higher percentage, researchers describe that this will have occurred more recently, such as when specific gene pools were developed or showed characteristics of particular lineages.
The study continues by explaining that ‘every disorder was seen in the mixed breed population’ and concluded that on the ‘basis of the data and analysis, the proportion of mixed-breed and purebred dogs affected by genetic disorders may be equal or differ, depending on the specific disorder’.
In particular, mixed breeds showed high percentages of being affected by cruciate ligament ruptures and researchers believe the reason for this is the crossing of certain breeds with varying skeletal structures.
The Kennel Club, who were pleased to read the study, believe that although the study was conducted overseas that it can ultimately affect all dogs.
Caroline Kisko, Kennel Club secretary explained: "This will ultimately impact all dogs, as there were no conditions found solely in purebred dogs. In addition, there was no single breed that was over-represented as a higher risk in the ten disorders assessed.
"Of the cancers assessed, specifically, there was no significant difference in risk between purebred and mixed breed dogs. Overall, the results indicated that genetic disorders were individual in their expression throughout the whole dog population, and that for some specific conditions there was a distinction between purebred and mixed breed dogs, and for other conditions, there was no difference to risk at all.
"We hope that the study will help people to make the right choices when buying a puppy and ask for relevant health checks no matter if they are purebred dogs or crossbreed dogs.”
The purebred dogs in the tests complied with the breed definition set out by the American Kennel Club.
- See more at: http://www.dogworl ... 4so8m.dpuf
http://www.dogworld.co.uk/product.php/95854